Our platform interrogates small RNA to identify molecular drivers of disease

AI-DRIVEN DISCOVERY DEFINES MOLECULAR PROFILES OF DISEASE CALLED SRNA-SIGNATURES

Small RNA are master regulators of gene expression found in blood and tissue

sRNA

SRNA-SIGNATURES CHARACTERIZE TARGETABLE PATHWAYS THAT ARE SHARED BETWEEN GROUPS OF PATIENTS WITHIN A DISEASE INDICATION

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Platform analyzes millions of sRNA features to create a signature that:

Classifies disease

Stratifies subjects

Predicts disease drivers

Designs RNA therapeutics

TARGETING THE SRNA-SIGNATURE CREATES A NEW CLASS OF RNA THERAPEUTICS

sRNA therapeutics are delivered using lipid nanoparticles and conjugates

High fidelity therapeutics derived from the sRNA-signatures enable unmatched precision

Advancements in lipid nanoparticle and conjugate chemistry enable drug delivery to multiple tissues

MACHINE LEARNING MINES AN EXPANDING MULTI-OMICS DATABASE TO ESTABLISH A MAP OF COMMON PATHWAY TARGETS ACROSS INDICATIONS

Disease Linkage

Discover novel drugs that treat multiple indications

Repurpose existing compounds including small molecules, protacs, mabs

Introduce new combinational therapies

Next: A big opportunity with small RNA (sRNA)